Background

The Drug Enforcement Administration has issued a temporary order placing the following benzimidazole-opioids in schedule I of the Controlled Substances Act.

- ethyleneoxynitazene

- methylenedioxynitazene

- 5-methyl etodesnitazene

- N-desethyl etonitazene

- Ndesethyl protonitazene

- N,N-dimethylamino etonitazene

- N-pyrrolidino isotonitazene

This order imposes the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who import, export, manufacture, distribute, reverse distribute, engage in research, conduct instructional activities or chemical analysis, or possess these substances. This order is effective as of Oct. 15, 2025, and will remain in effect until Oct. 15, 2027.

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