The Drug Enforcement Administration has issued a temporary orders that placing the following substances, their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, in Schedule 1 of the Controlled Substances Act.
- three 7-hydroxymitragynine-related substances (mitragynine pseudoindoxyl, MGM-15, and MGM-16), effective Aug. 26, 2026, through Aug. 26, 2028
- 1-(1-(1-(4-bromophenyl)ethyl)piperidin-4-yl)-5,6-dichloro-1,3-dihydro-2Hbenzo[d]imidazol-2-one (commonly known as 5,6-dichloro brorphine or SR-14968)
- 5,6-dichloro-1-(1-(4-chlorobenzyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
(commonly known as 5,6-dichloro desmethylchlorphine or SR-17018)
- 3-(3-(1-(1-(4-chlorophenyl)ethyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propanenitrile (commonly known as N-propionitrile chlorphine or cychlorphine)
- 8-(1-(4-chlorophenyl)ethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (commonly known as spirochlorphine or R-6890)
These orders impose the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who handle (import, export, manufacture, distribute, reverse distribute, engage in research or conduct instructional activities or chemical analysis with, or possess) or propose to handle these substances.
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