The Drug Enforcement Administration has issued a final rule that, effective Nov. 25, places the following substances, including their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, in Schedule I of the Controlled Substances Act.
- cyclopentyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopentanecarboxamide)
- isobutyryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylisobutyramide)
- para-chloroisobutyryl fentanyl (N-(4-chlorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide)
- para-methoxybutyryl fentanyl (N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4-yl)butyramide)
- valeryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylpentanamide)
This rule makes permanent the administrative, civil, and criminal sanctions and regulatory controls applicable to schedule I substances on persons who import, export, manufacture, distribute, possess, engage in research on, or conduct instructional activities or chemical analysis of these substances, which include the following.
- any person who engages in the above activities with respect to these substances must be registered with the DEA to conduct such activities
- all importation and exportation of these substances must be in compliance with 21 USC 952, 953, 957, and 958 and in accordance with 21 CFR part 1312
- all labels and labeling for commercial containers of these substances must comply with the requirements of 21 CFR part 1302
- any activity involving these substances that is not authorized under the CSA or the Controlled Substances Import and Export Act is unlawful and potentially subject to criminal penalties
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