Background

The Drug Enforcement Administration has announced its intent to issue an order temporarily including the synthetic opioids N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)propionamide (ortho-fluorofentanyl or 2-fluorofentanyl), N-(1-phenethylpiperidin-4-yl)-phenyltetrahydrofuran-2-carboxamide (tetrahydrofuranyl fentanyl), and 2-methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide (methoxyacetyl fentanyl) into schedule I of the Controlled Substances Act. Available information indicates that these substances have a high potential for abuse, no currently accepted medical use in treatment in the U.S., and a lack of accepted safety for use under medical supervision.

The temporary scheduling order will impose the administrative, civil, and criminal sanctions and regulatory controls applicable to schedule I substances under the CSA on the manufacture, distribution, reverse distribution, possession, importation, exportation, research and conduct of instructional activities, and chemical analysis of these substances. It will be effective on the date it is published in the Federal Register, which will be no sooner than Oct. 12, and will remain in effect for two years, with a possible extension of one year.

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